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Which medications can make acne worse?

Yoram Harth, MD
By Yoram Harth, MD | 2023-12-21

Certain drugs, including corticosteroids, lithium, anticonvulsants, barbiturates, androgenic steroids, DHEA, and medications that contain bromides or iodides, can cause true acne or acne-like eruptions.

More comment medications that make acne worse:

  • Oral corticosteroids (e.g., Prednisolone, Dexamethasone)
  • Anabolic steroids (e.g. Danazol, Stanozolol, Nandrolone)
  • Testosterone
  • Progesterone-only contraceptives (e.g., Progesterone only pill, Implanon, Mirena coil)
  • Lithium mood stabilizers
  • Anti-epileptics (e.g. Carbamazepine, Phenytoin)
  • Anti-tuberculous drugs (e.g., Rifampicin, Isoniazid, Ethambutol)
  • Immunosuppressant drugs (e.g., Ciclosporin, Azathioprine)

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